Biomarker Discovery by Novel Sensors Based on Nanoproteomics Approaches
نویسندگان
چکیده
منابع مشابه
Biomarker Discovery by Novel Sensors Based on Nanoproteomics Approaches
During the last years, proteomics has facilitated biomarker discovery by coupling high-throughput techniques with novel nanosensors. In the present review, we focus on the study of label-based and label-free detection systems, as well as nanotechnology approaches, indicating their advantages and applications in biomarker discovery. In addition, several disease biomarkers are shown in order to d...
متن کاملOvarian Cancer Biomarker Discovery Based on Genomic Approaches
Ovarian cancer presents at an advanced stage in more than 75% of patients. Early detection has great promise to improve clinical outcomes. Although the advancing proteomic technologies led to the discovery of numerous ovarian cancer biomarkers, no screening method has been recommended for early detection of ovarian cancer. Complexity and heterogeneity of ovarian carcinogenesis is a major obstac...
متن کاملComputational Approaches for Biomarker Discovery
Computational biology plays a significant role in the discovery of new biomarkers, the analyses of disease states and the validation of potential biomarkers. Biomarkers are used to measure the progress of disease or the physiological effects of therapeutic intervention in the treatment of disease. They are also used as early warning signs for various diseases such as cancer and inflammatory dis...
متن کاملAdvances in Genetics Systems-Based Approaches to Cardiovascular Biomarker Discovery
The pace of discovery of cardiovascular biomarkers seems to be slowing. Although important advances in the identification of molecular biomarkers have been made during the past decade, it is becoming apparent that their clinical relevance is limited and that advanced discovery methods are needed. There are 27 000 articles on cardiac biomarkers in PubMed. However, only a small number of these bi...
متن کاملProtein Array-based Approaches for Biomarker Discovery in Cancer
Biomarkers are deemed to be potential tools in early diagnosis, therapeutic monitoring, and prognosis evaluation for cancer, with simplicity as well as economic advantages compared with computed tomography and biopsy. However, most of the current cancer biomarkers present insufficient sensitivity as well as specificity. Therefore, there is urgent requirement for the discovery of biomarkers for ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Sensors
سال: 2012
ISSN: 1424-8220
DOI: 10.3390/s120202284